If you have multiple Effectors in a structure, you can run all of them at once by clicking the Run all effectors in this structure button:

Run all effectors in this structure button

Just as when you run a single Effector, you can select the "preview" mode to review any changes before they are applied to Jira.

Run dialogue for multiple effectors

Once the changes have been applied, you can review the operation on the Manage Effectors screen and, if necessary, revert any changes.

Manage Effectors - multiple effectors run at once